Role of Pharmacogenetics in Gastrointestinal Cancer

The Role of Evidence Based Nursing in Prevention of Gastrointestinal Side Effects of Chemotherapy in Children with Cancer

Introduction: Today, due to the broad spectrum of pediatric cancers are treated by the chemotherapy drugs, but these drugs have side effects and gastrointestinal toxicity is the most prevalent. One of the main roles of nurses is to better health through patient education and care for him. Evidence-based nursing is a process during which the nurse can use the available research evidence, their c...

The Role of Angiogenesis in Colorectal Polyps and Cancer, a Review

ABSTRACT           Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is known to play a key role in the initiation, growth and...

Association between pre-chemotherapy serum levels of vitamin D and clinicopathologic findings in gastric cancer

Background: To examine serum levels of vitamin D in newly diagnosed gastric cancer (GC) patients compared with normal subjects and any possible association with prognostic variables. Methods: One-hundred subjects (50 GC and 50 controls) were enrolled and serum vitamin D levels were assessed using ELISA. Based on two definitions, vitamin D was classified as a sufficient level (≥30 ng/dL) and op...

نقش رسپتور ملاتونینی در بیماران مبتلا به آدنوکارسینوم معده در استان مازندران

Background and purpose: According to recent studies melatonin has been known as a potent anti-oxidant with anti-oncostatic and cytoprotective properties. The gastrointestinal tract is the major source of melatonin in periphery. Therefore, many scientists suppose a protective role for melatonin in gastrointestinal tract. Also, there is a high rate of gastric adenocarcinoma in Mazandaran province...

Association of interleukin-1 gene polymorphism with risk of gastric and colorectal cancers in an Iranian population